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4.05pm BST

Brazil’s richest and most populous state, Sao Paulo, has warned its ability to care for seriously ill Covid-19 patients is on the verge of collapse as it runs perilously low on key drugs, according to a letter to the federal government seen by the Folha de Sao Paulo newspaper.

Sao Paulo state said it expects to run out of crucial intubation drugs, needed to sedate patients, in the next few days, the paper reported on Wednesday.

3.56pm BST

AstraZeneca said it respected the decision of Danish health regulators to stop using the company’s Covid-19 vaccine altogether because of a possible link to cases of a very rare type of blood clot.

“We recognise and respect the decision taken by Sundhedsstyrelsen (health agency) in Denmark,” the company said in a statement, adding it was a matter for each country to decide over vaccination programmes based on local conditions.

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Source: The Guardian